International cooperation boosts traumatic brain injury research

Cai Wenjun
No breakthrough occurred in research on traumatic brain injury in 2019.
Cai Wenjun

Although no breakthrough occurred in research on traumatic brain injury in 2019, several substantial advances have been made, particularly in large database analyses of patients' characteristics, biomarker monitoring and stratified treatment of cognitive impairment after traumatic brain injury, said local medial experts on an article published by The Lancet Neurology.

Dr Jiang Jiyao from Renji Hospital led his team to study the clinical discovery and development on traumatic brain injury in the world this year and published the evaluation article on the invitation of the journal. 

Jiang said international cooperation is a must to boost traumatic brain injury research and developing countries should make better use of their big number of cases and clinical experiences to lead multicenter clinical research and big data study on patients with traumatic brain injury.

The article said the discovery of biomarkers glial fibrillary acidic protein (GFAP) and tau presented new perspectives in the area. GFAP can improve detection of traumatic brain injury while tau in plasma can be used as a diagnostic and prognostic biomarker for acute and chronic traumatic brain injury.

Jiang’s team has completed big data research with the EU on traumatic brain injury and is working on two US-registered multicenter clinical study, which is expected to help improve treatment direction for China and the whole world and help reduce mortality and disability for patients.

International cooperation boosts traumatic brain injury research
Ti Gong

Dr Jiang Jiyao (right) from Renji Hospital discusses a case with colleagues.


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